GNA Biosolutions is engaged in an ongoing collaboration with the Bundeswehr Institute of Microbiology (the scientific center for biological medical biodefense of the German Armed Forces), Madagascar’s Ministry of Health, and the Institut Pasteur Madagascar. The partners aim to improve plague (Yersinia pestis) diagnostics in Madagascar (ENhancing Outbreak ResponSe CapacitiEs in Madagascar, ENdORSE).
The objectives of the ENdORSE project, as defined by a partners, are to strengthen plague diagnostics in the Malagasy reference laboratory; to implement a training capability for mobile diagnostics in a field laboratory, and the development of a molecular diagnostic system including portable instrumentation and a ultrafast test, which could be used to detect Yersinia pestis infection in remote outbreak locations in Madagascar. By quickly and reliably differentiating infected from non-infected patients, quarantine measures could be more targeted, plague transmission could be curbed, and unnecessary antibiotic therapies avoided.
Preliminary data for an ultrafast plague assay being developed on GNA’s proprietary Pulse Controlled Amplification (PCA) platform will be presented at the Medical Biodefense Conference to be held in Munich, Germany, from 28 to 31 October 2018. On-site assessment for future field tests in Madagascar are scheduled for November 2018.
ENdORSE Partners at the inaugural meeting, June 2018